The High Resolution Photon Counting System (HRPCS) is a true single photon counting camera system which offers the unique ability to capture and integrate an image in real time. The HRPCS is ideal for extremely low photon emission applications such as bio-luminescence and weak fluorescence. The system comprises of the Photek Single Photon Counting Camera System, Camera Control Unit, IFS32 Data Acquisition and Image Processing Software and optional dark box. X-ray and vacuum imaging camera options are available.